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Polynucleotide in Singapore

Renews, repairs, and revitalises your skin for natural, youthful radiance.

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Cellular Repair for Younger, Healthier Skin

Polynucleotide (PN) treatments use purified DNA fragments designed to repair, regenerate, and restore skin health. These molecules attract moisture, support collagen regeneration, and promote tissue healing at a cellular level. As a result, PN therapy improves skin texture, firmness, and overall vitality.

Polynucleotides work by stimulating fibroblasts—cells responsible for collagen and elastin production. This leads to stronger, smoother, and more resilient skin over time. Because PN treatments strengthen the skin structure instead of simply masking symptoms, they deliver long-lasting, biologically driven results.

Suitable for all skin types, polynucleotide injections are ideal for those experiencing early signs of ageing, dehydration, or skin damage. They provide gentle yet powerful rejuvenation without drastically altering facial features.

How does Polynucleotide work?

Polynucleotides activate the skin’s natural regeneration process by stimulating fibroblast activity, enhancing cellular repair, and boosting collagen and elastin synthesis. They improve microcirculation, deeply hydrate tissues, and restore weakened skin structures. Over time, PN increases skin density, reduces inflammation, and improves overall skin quality for a healthy, youthful glow.

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Treatment Benefits

Polynucleotide Advantages

  • Fine lines and early wrinkles

  • Dehydrated or thinning skin

  • Loss of elasticity and firmness

  • Dull or tired-looking complexion

  • Acne scars and textural irregularities

  • Redness, inflammation, and sensitive skin

What to Expect During Treatment

  • Skin assessment and mapping of injection points

  • Gentle micro-injections with minimal discomfort

  • Mild swelling or small bumps that settle within hours

Potential Risks

Polynucleotide Singapore has minimal side effects, which will be explained prior to the procedure by Dr. Mendis.

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What skin issues can Polynucleotide fix?

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Understanding Polynucleotide

How PN Supports Skin Regeneration

Polynucleotides are biocompatible DNA fragments that help restore the skin’s natural healing and regenerative abilities. They support deep hydration and cellular repair, making the skin healthier from within.

By boosting fibroblast activity, PN enhances collagen and elastin production—key components for firm, youthful skin. This means improved texture, reduced fine lines, and overall skin strengthening.

Because PN improves the skin’s biological functions rather than simply filling or lifting, it delivers natural, gradual, and long-lasting rejuvenation.

Polynucleotide Treatment Procedure

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Consultation

Identify skin concerns and ideal treatment areas.

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Preparation

Prepare the skin for a comfortable session.

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PN Injections

Administer micro-injections across targeted zones.

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Recovery

Apply calming post-care for quick healing.

Aesthetic and Medical Use of Polynucleotide

A Regenerative Solution for Beauty and Skin Repair

Aesthetically, polynucleotide injections are widely used to rejuvenate ageing or damaged skin. They improve elasticity, brighten the complexion, soften wrinkles, and refine texture. PN is ideal for delicate areas such as under the eyes, where fillers may not be suitable, making it a popular choice for natural, subtle enhancement.

Medically, PN supports tissue repair, reduces inflammation, and strengthens compromised skin barriers. It is often used to support recovery from acne damage, chronic dryness, and skin weakened by sun exposure or ageing. Its regenerative properties make it beneficial for patients needing long-term skin health restoration.

Whether used for subtle anti-ageing, hydration, or cellular repair, polynucleotides offer one of the most advanced and biologically effective solutions in modern aesthetic medicine.

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Frequently Asked Questions

  • The salmon DNA used in Polynucleotide is purified to be free from other components such as proteins which may trigger an immune response. Researchers also found that salmon DNA is very safe and compatible in the human body without causing any adverse side effects. 

  • it takes up to 4 weeks to see any visible improvements in your skin, approximately 4 weeks for PDRN to take effect and repair the skin from the inside.

  • The treatment is best done 3 to 4 times, 2 to 4 weeks apart. Afer that, treatments can be repeated once every 6 – 9 months for maintenance.​

  • The effects are long-lasting and sustainable

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Consult Our Doctor

DR. ROHAN MENDIS

With over 20 years of experience in aesthetic medicine, Dr. Mendis personally consults and treats every patient at Mendis Aesthetics. His patient-first approach ensures your treatment plan is safe, evidence-based, and tailored to your individual needs.

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Ready to Look and Feel Your Best?

Take the first step towards results you can feel confident about.

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